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Parallel research on NAD biology (e.g., precursors like NR/NMN) reinforces the centrality of NAD to mitochondrial output and recoverymechanistically aligned with 5-Amino-1MQs NNMT inhibition (Cant et al., Cell Metabolism )

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Figure 10 Phylogenetic analysis highlights a marked difference in the evolution of anaerobic metabolism between closely-related pathogens

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