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Autophagy is a catabolic process activated during a number of metabolic stress conditions, such as nutrient deprivation [100]

This combination has been investigated in preclinical models examining synergistic effects on tissue recovery and inflammatory signaling pathways

4), 2SS1 and 3KGLwere retrieved from the Protein Data Bank (PDB) for structural analysis

Topical diclofenac therapy for osteoarthritis: A meta-analysis of randomized controlled trials

In summary, oxidative stress can cause the progress of fibrotic diseases through these damages (Antar et al., 2023) (Figure 2)
