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Each animal was individually placed on a 110 cm long and 1.5 cm wide wooden bar that was inclined at an angle of 60 from the ground, and the rats were given 60 s to walk the beam

Safety outcomes All adverse events (AEs), serious AEs (SAEs), significant clinical laboratory abnormalities and changes in vital signs are being reported for all groups from screening to the end of the study among all randomised patients

However, we always allow extra time for the entire appointment to ensure you have a thorough consultation and we can answer any questions you may have beforehand

Furthermore, significant accumulation of TZ in the brain following administration indicates its ability to cross the bloodbrain barrier, highlighting its considerable promise for PD treatment [183]