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Psychiatry Res 151:145150 Michel TM et al (2010) Increased xanthine oxidase in the thalamus and putamen in depression

MYC regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

Progress in growth factor research

Elevated levels of succinate in the gut are a known feature of IBD and other conditions of intestinal inflammation and microbial imbalance (dysbiosis) (164, 165), as evidenced by elevated serum and intestinal succinate levels and SUCNR1 expression in Crohn's disease patients (166)

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Glutathione acts as a primary shield, neutralizing these molecules before they can cause significant damage
