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A transgenic mice study stated that the overexpression of IGFBP-3 is associated with impaired glucose tolerance [177, 178]
Data from the 2021 Nature Aging paper are particularly illuminating on this point
regulation of oxidant producing enzymes, such as NOXs, and, possibly, the subcellular compartment in which ROS is produced
however, the current literature is conflicting with some studies demonstrating no significant difference between controls and those with BD
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