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Chen, S., Hanning, S., Falconer, J., Locke, M

A key concept for understanding this interface is that while health-damaging behaviors (e.g.: poor diet, excessive alcohol consumption, sleep deprivation and circadian disruption) contribute to allostatic load and the many consequences of such behaviors on triggering and exacerbating these illnesses, it is increasingly recognized that health-promoting behaviors that protect mitochondrial metabolism and energy regulation are an essential component of successful allostasis

Therefore, low CPT activity and diminished l-carnitine levels may contribute to the development of mitochondrial metabolic inflexibility [37,38,39,40]
Some research has suggested a possible connection between L-carnitine supplementation and increased risk of atherosclerosis, a condition in which the arteries harden due to buildup of fats, cholesterol, and other substances

doi: 10.1177/0883073895010002S02
