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Xie Y, Hou W, Song X et al (2016) Ferroptosis: process and function

This pathway entails the antioxidant metabolites: ascorbate, glutathione and NADPH along with the enzymes linking them

[DOI] [PMC free article] [PubMed] 21.Liu YMC

15 The decrease in enzymes related to NAD + de novo synthesis is due to the inhibition of the activity of PPAR coactivator 1 (PGC-1), which is a crucial determinant of renal recovery from AKI

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