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Description
This occurs via the Bcl-2 family of proteins and the cysteine protease caspase family

Lysosomal regulation of inter-mitochondrial contact fate and motility in Charcot-Marie-tooth type 2
Naliyadhara N, Kumar A, Kumar Gangwar S, Nair Devanarayanan T, Hegde M, Alqahtani MS, Abbas M, Sethi G, Kunnumakkara A
This damage allows low-density lipoproteins to enter the tunica intima, where they are oxidized and engulfed by macrophages to form foam cells

Wang M., Chen J., Zhang R., et al., Design, Synthesis and Bioactive Evaluation of Geniposide Derivatives for Antihyperuricemic and Nephroprotective Effects, Bioorganic Chemistry 116 (2021): 105321, 10.1016/j.bioorg.2021.105321

the cell transfers dehydroascorbic acid to the endoplasmic reticulum, which oxidizes the environment
