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This analysis also revealed that proliferation and differentiation are associated with increased glutathione levels and decreased amounts of hypotaurine and taurine, supporting proposals that organosulfur compounds play an important role in these processes

Excessive alcohol consumption also reduces glutathione production and increases the demand for this master antioxidant in detoxification processes

Additionally, it was demonstrated that EGT deficiency exacerbates the phenotype of the extremely sensitive mutant strain lacking Yap1 too ( egtA yap1 ) during treatment with oxidative stressors or metals

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