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Simply reducing load doesn't create that stimulus

McDole JR, Wheeler LW, McDonald KG et al (2012) Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

To interfere with the FOXO4-p53 interaction, we therefore designed a cell-permeable peptide comprising part of the p53-interaction domain in FOXO4 (Fig

In particular, B12 and B9 deficiencies can cause neural tube defects, which can prevent the spinal cord or brain from developing properly

Lifestyle and dietary modifications are crucial for managing reflux alongside Wegovy: Eat smaller, more frequent meals rather than large portions, which can overwhelm your already-slowed digestive system Avoid lying down within 3 hours of eating to reduce reflux risk Identify and limit trigger foods such as caffeine, alcohol, chocolate, spicy foods, and high-fat meals Stay well-hydrated but avoid drinking large volumes with meals Elevate the head of your bed by 15-20cm if you experience night-time symptoms Maintain good posture during and after meals If reflux symptoms worsen or new symptoms develop whilst taking Wegovy, contact your GP