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However, tamoxifen exerts anti-tumor efficacy independently of ER expression through various mechanisms, such as those associated with oxidative stress [90]

p53 Activation via MDM2 Blockade with Nutlin3a Sensitizes Primary Blast Crisis Chronic Myeloid Leukemia Cells and Stem/Progenitor Cells to ABT-737- and Nilotinib-induced Apoptosis

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van BrummelenEMRosWWolbinkGBeijnenJHSchellensJH.Antidrug antibody formation in oncology: clinical relevance and challenges