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The most common are gastrointestinal: nausea, vomiting, diarrhea, decreased appetite, and constipation

Other metals which are present in the environment as industrial pollutants are not able to generate free radicals by shuttling between contiguous oxidation states but it is known that organisms exposed either in their natural environment or in toxicological experiments show signs of oxidative stress, and some metals, such as As, Cd and Hg, are also carcinogenic to humans

Abstract The yellow polyphenolic pigment known as curcumin, originating from the rhizome of the turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as in cooking and food coloring

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Today, they represent an estimated 510% of the global pharmaceutical market, with continued growth driven by ongoing research and clinical interest (Grandview Research, 2023)

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