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Beyond traditional viability assays, the system captured mechanistic endpoints including mitochondrial dysfunction, oxidative stress, and fibrosis-related pathways, highlighting its suitability for mechanistic studies, biomarker discovery, and safety risk assessment

Med 21 , 757 (2023)

Recent breakthrough research in 2024 demonstrated that 5-amino-1MQ combined with exercise training in aged murine models produced enhanced adaptations compared to exercise alone, with grip strength improvements of approximately 60% and alterations in daily locomotor activity patterns with modified recovery kinetics

High ROS activities and associated oxidative stress in the follicular fluid and serum from patients with endometriosis have the ability to damage gametes and embryos (109)