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As our comprehension of cancer genomics expands, clinical trials are increasingly tailored to individual patients, often based on the unique biology of their tumors

doi: 10.1152/physiolgenomics.00071.2006

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The authors argue that this is a missed opportunity because the TDLN is a place where tumor antigens are first processed and presented to the immune system, and where the balance between immune activation and immune tolerance may be decided early

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DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD