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Description
A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase
The maximal activity of the dimeric macrocycles was observed at around 100 nM
Darmon, N
N.MorrisA
Mitochondrial PDH catalyses the oxidative decarboxylation of pyruvate to acetyl-CoA, which can then enter the Krebs cycle to generate hydrogen carriers
It protects against oxidative stress, which is associated with diseases such as heart disease, cancer, diabetes, and neurodegenerative diseases (like Alzheimers and Parkinsons)
