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Elevated lipopolysaccharide (LPS) translocation and endotoxemia are also reported in NIDDM, which, like obesity, may contribute to reduced inflammation that contributes to the formation of insulin resistance (Wang et al., 2012)

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Acute and long-term administration of palmitoylcarnitine induces muscle-specific insulin resistance in mice

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[131] indicates that LC supplementation increases plasma concentrations of insulin-like growth factor-1 (IGF-1) and activates the corresponding signaling pathways
