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However, severe symptoms can be observed in the cases of higher doses
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Ophthalmopathy : Assessment of eye involvement, including exophthalmos, diplopia, and severity of thyroid eye disease
Intravenous drugs can also be less painful than oral medications
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In humans, the C-oxidation of nicotine to cotinine is the major pathway of nicotine metabolism and cotinine is used as a biomarker for nicotine exposure 40
