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Notably, in addition to subcutaneous injections, the first oral Lp(a)-reducing small molecule, Muvalaplin, has also recently achieved a breakthrough, with a Phase I clinical study demonstrating that daily oral doses of Muvalaplin over a 14-day period reduced blood Lp(a) levels by up to 65 per cent [238]
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doi: 10.1126/science.1120411
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(A) The rose petal pattern characterized by brown projections with pigmented borders and dichotomized vessels originating at the base
