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Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2.4 mg for weight management: a randomised, controlled, phase 1b trial

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showed that metastasis-associated fibroblasts (MAF) expressed high levels of CD38 and activated macrophages into a pro-tumoral M2-like macrophage [52]