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[DOI] [PMC free article] [PubMed] [Google Scholar] 256.Roybal KT, Williams JZ, Morsut L, Rupp LJ, Kolinko I, Choe JH, Walker WJ, McNally KA, and Lim WA (2016)

Efficient drug screening and nephrotoxicity assessment on co-culture microfluidic kidney chip

Because of this loss of binding, the C-terminus of importin does not coil around the Ran-GDP:RanBP1 complex as it does with Ran-GTP, but instead remains flexible, likely resembling unliganded importin 45,46 , which has proven intractable for cryo-EM single-particle analysis

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Treatment was primarily limited to short-acting bronchodilators delivered on an as-needed basis

Finally, some polymers, such as polyacrylic acid, alginates and hyaluronic acid, adhere by physically entangling with mucin fibres and are commonly used for mucoadhesive particles coatings 62,143