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10.1111/j.1530-0277.1994.tb00906.x Alcohol

How Acne Supplements Work From Within Unlike skincare products applied externally, acne supplements work internally to: Regulate hormone levels to prevent excess sebum production Reduce systemic inflammation that contributes to skin redness and irritation Detoxify the liver and gut, where hormone metabolism occurs Improve the immune response to reduce acne-causing bacteria When used consistently and combined with lifestyle changes, supplements can provide long-term relief from persistent hormonal breakouts

10.1038/s41596-021-00602-5 121 ZhangX.JinJ.LiuC.ZhouM.HeY.WangF.et al (2021)

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Most people feel the immediate effects (energy, mental clarity, hydration) within 30 minutes to a few hours, and a more general lift over the next 1 to 3 days
