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CHAC1 emerges as a key stress-responsive effector, transcriptionally upregulated via the ATF4-CHOP axis during endoplasmic reticulum stress and amino acid deprivation

Therefore, changes in gut microbial community structure and diversity are also one of the key factors leading to the onset and development of CVDs, as revealed by accumulating evidence (25)

These findings demonstrated the reduction of extracellular tissue tension (Fig

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doi: 10.3390/nu12072033

However, a few case reports have advised caution in asthma patients receiving NAC for paracetamol poisoning, as severe bronchoconstriction was observed following IV infusion (156)