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Sociodemographic characteristics Diagnosis (vitamin B12 deficiency or pernicious anaemia), age, sex, education level, employment status, country of residence (England, Wales, Scotland, Northern Ireland, Republic of Ireland), region of residence (nine English regions, according to the Office for National Statistics, Wales, Scotland, and Northern Ireland) were assessed using the questions in Supplementary Table S1

In the U.S., 58% of obese adults have high blood pressure, a risk factor for heart disease, and approximately 23% have diabetes

Inflammatory states: Acute and chronic inflammatory conditions can increase haptocorrin levels, leading to elevated total B12 measurements

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Collectively, these investigations suggested the plausibility of modulating the rate of drug release as well as specifically targeting different GSTs by modifying the sulfonamide moiety 128

thus, cortical bone fragility is also a susceptibility factor for fractures
