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Correspondingly, a study has recorded that administering folic acid (at a dosage of 120 mg per 500 kg of body weight) for 21 days led to the downregulation of several genes linked to immune function and inflammation (PIM1, SOCS3, ATP12A, KIT, LPL NFKBIA, DUSP4, ZC3H12, ESPNL, TNFAIP3) (165)

For many generally healthy adults who are using typical doses, the answer is often no, as long as you are working with a licensed healthcare provider who knows your medical history

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