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Conversely, there is no evidence for accumulation of valproyl-CoA in brain tissue, suggesting that the effects of VPA in the CNS are independent of the formation of this metabolite [80]

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doi: 10.1038/s41591-018-0052-4 159 ZachariasNMMcCulloughCShanmugavelandySLeeJLeeYDuttaPet al

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