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Immune mechanisms and the impact of the disrupted lung microbiome in chronic bacterial lung infection and bronchiectasis

Accordingly, the GSH/GSSG redox couple can readily interact with most physiologically relevant redox couples, undergoing reversible oxidation or reduction [7]

Thioredoxin regulation of the glucocorticoid receptor through association at the DNA binding domain has also been reported [34] and this too is influenced by ROS

this chelation reverses the oxidative process in cells by reducing free iron, thereby inhibiting ferroptosis (Orino et al., 2001)

[DOI] [PubMed] [Google Scholar] 76.Zou C.-G., Banerjee R