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Furthermore, Six of the studies which clarified high amount of folate might be a protective factor for CRC in all three MTHFR C677T genotype, especially in TT genotype

[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Pinho-Ribeiro F.A., Verri W.A., Jr., Chiu I.M

Before such applications can become widely available, in vitro and in vivo studies that examine efficacy and safety issues (dose, off-target effects) must be accomplished
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