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These metabolic disturbances activate several pathogenic pathways that contribute to neuronal dysfunction and death, ultimately manifesting as DPN

Elevated homocysteine is an arterial poison

Am J Hematol 92(1):119-120, 2017
noted that the acid condensation product of indole-3-methanol is an effective inhibitor of FMO3, which can decrease human plasma TMAO levels (86)

D.ComptonW

Bojanowski, MT
