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Chronic HCV rashes are more challenging to treat due to the ongoing nature of the disease

Our model also accounts for the efficacy of commonly-used treatments of CVS, including mitochondrial-targeted therapies, propranolol (beta blockade interferes with catecholamine-induced release of calcium via the RYR2 calcium channel (101), and amitriptyline (used for peripheral neuropathy)

Taken together, these results suggest that hlh-11 inactivation initiates fat breakdown to support the energetic demands of parental worms, resulting in fat loss from these animals

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