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In eukaryotes, TML is the product of lysosomal or proteasomal degradation of proteins such as calmodulin, myosin, actin, cytochrome c, and histones, which contain N -methylated lysine residues from post-translational modification (Strijbis et al., 2010)

Their guts exhibit an increase in Lactobacillus, Streptococcus, Esherichia, Shigella and Enterococcus species, concomitant with a reduction in Faecalibacterium, Subdoligranulum, Roseburia, Eubacterium rectale and Bacteroides fragilis species, the latter group known to regulate T-cell functions in the gut mucosa with consequent anti-inflammatory effects and protection of the gut barrier [7, 14]

[DOI] [PubMed] [Google Scholar] 91.Caviglia D., Scarabelli L., Palmero S

A.et al (2013)

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Physicians who performed baseline and outcome assessments were also blinded to the randomization status