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SIRT3 decreases the accumulation of PC in adipocytes through deacetylating CPT2 CPT2, located on the inner mitochondrial membrane, converts LCACs into LC and long-chain acyl-coenzyme As (acyl-CoAs) to facilitate FAO

[DOI] [PubMed] [Google Scholar] 40.Balasubramanian N., Srivastava A., Pawar N., Sagarkar S., Sakharkar A.J

But this compound also occurs naturally in some foods, particularly animal products

doi: 10.1016/j.biochi.2016.01.003 237 WangHRongXZhaoGZhouYXiaoYMaDet al

Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer

Cardiotoxicity Two small RCTs: Conflicting results, one showed no effect, one showed reduced cardiac events