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Mishra et al., 2011)

In addition to this, treatment of A549 and H3122 cells with SAG caused an increase in intracellular Fe 2+ concentration, ROS levels and MDA content as well as a decrease in GSH content, which was thus shown to also trigger ferroptosis in lung cancer [217]

182 Cancer As individuals age, the risk of cancer increases, partly due to immune senescence, which involves a decline in immune system function and contributes to tumorigenesis (Fig
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