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Glutathione promotes exercise performance Some studies have shown Glutathione can improve athletic performance, reduce fatigue, and lower blood lactic acid levels

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Sustained ER stress upregulates the C/EBP homologous protein (CHOP), a predominant pro-apoptotic transcription factor in ER, triggering downstream cascade responses (Kim et al., 2018)

10.1016/j.biopha.2020.110119 116 TaoJ.ZhangM.WenZ.WangB.ZhangL.OuY.et al (2018)

Transcriptionally inactive SREBP proteins are retained in the membrane of the endoplasmic reticulum

Normal distributions were applied to all inputs, with the mean obtained from the previous optimisation procedure, and coefficient of variation of 180%