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These paradoxical results could be observed in some other studies, such as the Keap1-Nrf2 axis in acute lung injury, in which Keap1 expression increased in some animal and in vitro experiments ( in vitro experiments (Zheng et al., 2021

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Inhalation of PM exacerbates respiratory symptoms in patients with chronic airway diseases, but the mechanisms underlying this response remain unclear

Nicergoline induced vasodilation and increased cerebral blood flow [69]

Using patient self-reports to study heterogeneity of treatment effects in major depressive disorder

In addition, antioxidants have also been shown to be capable of reversing certain altered biochemical variables and this ability enhances its potential to provide for optimal therapeutic benefits while causing fewer or minimal side effects