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Thus, one may conclude that repeated administration of R
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GAA administration significantly upregulated the expression of GPX4, SLC7A11, and NRF2 in the hippocampus of APP/PS1 transgenic AD mice, inhibited neuronal ferroptosis, and improved cognitive function in these mice

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Such co-expression to produce separate proteins can be achieved, for example, using an internal ribosome entry site (IRES) or a self-cleaving peptide to link the genes [47]
