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For skin and tissue-focused peptide dosing, see our GHK-Cu injection dosage guide

This occurs through multiple mechanisms

A large reduction of red blood cells means that essential oxygen is not getting to all the tissues and organs that need it

Excessive NAM depletion directly reduces the substrate supply for NAD+ synthesis, leading to decreased intracellular NAD+ levels

A temporary feeling of warmth in the area

People can become deficient when they are not eating enough vitamin B12 rich foods, or their bodies may struggle with absorbing the vitamin
