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Preoperative administration of Ganoderma lucidum polysaccharides improves immune function, creating more favorable conditions for surgery [281]

Latest clinical studies have reported higher expression of markers of astrogliosis and microgliosis, as well as of both peripheral and central neuroinflammation, in young AD cases as compared with old ones, indicating that all these phenomena are prominent at the earliest AD stage, and can even decrease with aging

J Neural Transm (Vienna) 129(8):10771089 Funakoshi H, Kanai M, Nakamura T (2011) Modulation of tryptophan metabolism, promotion of neurogenesis and alteration of anxiety-related behavior in tryptophan 2,3-dioxygenase-deficient mice

There is no conflict between the two

Ggt1, which is expressed at high levels in renal proximal tubules, is considered the central enzyme that maintains the systemic redox balance by hydrolyzing glutathione to glutamate and Cys-Gly via the glutathione pathway