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Although cytokines and chemokines measured in experimental inflammatory models have shown a great promise as biomarkers, their clinical utility has been limited by inconsistent results across studies, likely due to variations in sample types (e.g., serum, skin biopsies) and patient heterogeneity [229]

9 Animal experiments have shown that dual ALDH2 knockout in the gut and liver synergistically reduces alcohol preference and intake relative to knockout in one of these organs

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Therapeutically, to prevent medical error or at least reduce side effects often seen in chronic disease management, AI can help develop personalized treatment strategies (e.g., medication combinations and dosages) by comparing large datasets to identify treatment that best fit patients based on their specific profiles [233]

Perioper Med (Lond) 2012;1:6