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These pathways exhibited high statistical significance and impact scores, underscoring a generalized disruption in central carbon metabolism in lipedema

The related biological roles involved the metabolic process of glutathione derivatives, binding of oligopeptides, and transferase activity that transfers alkyl or aryl groups (excluding methyl groups), peptide binding, modified amino acid metabolic process, sulfur compound biosynthetic process, and antigen processing and presentation of endogenous peptide antigen

To reduce the oxidative effect of toxins and prevent the ability of oxidants to acquire electrons from other structures and cause DNA damage, antioxidants donate electrons to oxidant species

These are all peptides and play important roles in biological systems

mRNAs, proteins and the emerging principles of gene expression control

TABLE 4 Provided herein are methods for preparing a conjugate comprising a protein (e.g.,an antibody or antigen-binding fragment thereof) and one or more immunomodulating oligonucleotides linked via one or more glutamine residues as shown in the structure of Formula (A), (A1), (A2), (B), or (B1)