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Phlorizin, a naturally occurring flavonoid found in the bark of pear ( Pyrus communis ), represents the lead compound for synthetic analogs used in the treatment of type 2 diabetes (the therapeutic class of SGLT2 inhibitors, such as dapagliflozin, canagliflozin, empagliflozin)

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The resulting mitochondrial iron overload might cause mitochondrial damage via iron-catalyzed oxidation reactions [37]
Aripiprazole, a comprehensive review of its pharmacology, clinical efficacy, and tolerability

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