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Furthermore, several studies suggest that IGF-1 may indirectly affect the CV system by increasing insulin sensitivity (113, 122124)

The study demonstrated that glutamine metabolism inhibition causes early recruitment of activated T-cells, reduced frequency of immunosuppressive myeloid cells, and enhanced antimycobacterial activity of macrophages concomitant with upregulation of host-protective metabolic pathways

10.1016/j.bmc.2014.05.025

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Temporal dynamics of glyoxalase 1 in secondary neuronal injury

However, this treatment may cause iron overload as each unit of transfused blood contains ~200250 mg Fe [31]