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Simultaneous quantitation of kavalactones in kava dry extracts: Comparison of multi-standards and single standard validation approaches

In HeLa tumor-bearing mice, drug cytotoxicity was significantly increased and tumor hypoxia was enhanced

[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Ndagijimana M., Laghi L., Vitali B., Placucci G., Brigidi P., Guerzoni E

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For this reason, MEL and its metabolites may serve as effective therapeutic agents in iron-induced oxidative stress, for example, in patients with Parkinsons and Alzheimers disease, in whom higher levels of iron and lipid peroxidation have been observed in the brain compared to healthy individuals [76,77]