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Antisense technology and RNA interference (RNAi) share a common goal of down-regulating gene expression, yet they employ distinct mechanisms

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However, in M2-type microglia, the binding of 2-AG to CB2R enhances the expression of the anti-inflammatory cytokine IL-10 and the solubilizing factor lipoxin-4 (LXA4) (162)

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(2019) 15:e1007672

Another consequence of PK deficiency is the accumulation of glycolytic intermediates, such as 2,3-biphosphoglycerate (2,3-BPG)
