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The PRMT5 inhibitor PF-06939999 inhibited the proliferation of non-small cell lung cancer (NSCLC) in cells and animal models and dose-dependent reduced symmetrical dimethylarginine (SDMA) levels
Del Rio D, Zimetti F, Caffarra P, Tassotti M, Bernini F, Brighenti F, et al
Muscle Nerve, 42(5), 739748 (2010)
doi: 10.3945/ajcn.115.113613
Acylcarnitines are then translocated across the inner mitochondrial membrane by the carnitine acylcarnitine translocase (CACT, SLC25A20 gene) [3]
