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It is a co-factor for methionine synthase, an enzyme involved in the methylation cycle, which is crucial for the metabolism of amino acids and the production of neurotransmitters

It has been shown to upregulate growth factors such as VEGF and enhance collagen formation in cultured cells

And reduce your B12 intake to lower the risk for toxicity

This age-related decline parallels other measurable changes like the loss of lean mass and bone density that a DEXA scan can quantify

doi: 10.1016/j.enzmictec.2022.110149 48 PontrelliSChiuT-YLanEIChenFY-HChangPLiaoJC

A common genetic variant, known as Val66Met (rs6265), affects how efficiently the brain produces and secretes BDNF