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DOI: 10.4274/jcrpe.3690 32

These early safety and pharmacokinetic studies preceded Phase 2 dose-ranging work in 20042006 and the Phase 3 pivotal trials that began in 2006

Accordingly, GPx-1 is a crucial antioxidant enzyme involved in preventing the harmful accumulation of intracellular hydrogen peroxide

Quantitative PCR with reverse transcription RNA was isolated from PBMCs and the human brain endothelial cell line hCMEC/d3 (cat

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