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Elantary R, Othman S

For example, mutations in genes related to tyrosine or phenylalanine, genes related to mitochondrial acyl-CoA synthesis, and certain genes related to heart disease

For instance, the mitochondrial shuttle-system allows the transport of fatty acids, as acylcarnitines, from the cytosol into the mitochondrial matrix where these nutrients are oxidized for ATP production

However, during high-fat diet (HFD) feeding, obesity and insulin resistance, the accumulation of medium-chain and long-chain acylcarnitines due to incomplete -oxidation may negatively regulate the expression of nuclear-encoded mitochondrial genes, further reducing mitochondrial number and function and creating a vicious metabolic cycle [33]

CrossRef Increased Risk of NAFLD in Adults with Glomerular Hyperfiltration: An 8-Year Cohort Study Based on 147,162 Koreans Dae-Jeong Koo, Mi Yeon Lee, Inha Jung, Sun Joon Moon, Hyemi Kwon, Eun-Jung Rhee, Cheol-Young Park, Won-Young Lee, Ki Won Oh, Se Eun Park Journal of Personalized Medicine.2022

Preventive effects of bovine colostrum supplementation in TNBS-induced colitis in mice