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To generate the ARX-Mut construct, a 14-bp sequence at the ATF4 binding site within the ARX promoter was deleted, introducing a frameshift mutation

This sex difference is effectively nullified by NAC, in the sense that the final accumulated beta power at hour 6 during SD in the NAC condition was (non-significantly) higher in females (1917 mV 2 min

Through this, LDL binds LDL receptors (LDLRs) on the plasma membrane to be stored as lipid droplets in the cytoplasm, thus decreasing the concentration of circulating LDL [8]

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