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EASI, SCORAD, and the extent of skin lesions were negatively correlated with C6 SCFAs, specifically caproic and isocaproic acid, and positively correlated with indoxyl and leaky gut-related biomarkers (LBP, Reg3A, IL-10, and IL-22)

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For this reason, the conjugation of specific chain length acyls with L-carnitine creates very particular species of acylcarnitines that reflect any inborn errors of metabolism

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