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Availability of data and materials The sequence read data of gut microbiome for characterizing TMAO producers (BioProject:PRJNA589723) were all available on NCBI sequence read archive (SRA) database (SRA accession numbers:SRR10465787-SRR10466048)

Triglycerides are particles in the blood that transport fat
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G.et al (2010a)

UBIAD1, a cholesterol-synthesizing enzyme, has been identified as the underlying mechanism responsible for MK-4 accumulation in tissues by catalyzing phylloquinone conversion into MK-4 [21]